Stems Cells and the Pathways to Aging and Cancer
نویسندگان
چکیده
The aging of tissue-specific stem cell and progenitor cell compartments is believed to be central to the decline of tissue and organ integrity and function in the elderly. Here, we examine evidence linking stem cell dysfunction to the pathophysiological conditions accompanying aging, focusing on the mechanisms underlying stem cell decline and their contribution to disease pathogenesis.
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ورودعنوان ژورنال:
- Cell
دوره 132 شماره
صفحات -
تاریخ انتشار 2008